Demerdash Hospital was established in 1928 with a donation from Mr. Abdel Rahim El Demerdash Pasha, and the Faculty of Medicine was established at Ain Shams University in 1947 and was called Demerdash Faculty of Medicine and was affiliated with Fouad I University (currently Cairo University), then it was joined to Ain Shams University in 1950 to be the third Faculty of Medicine in Egypt After the medicine of Cairo and medicine of Alexandria, and attached to it a teaching hospital, the Demerdash Hospital, which includes most of the surgical departments.

The buildings of the Freedom Shelter, adjacent to the hospital, were chosen as the headquarters for the scientific departments: anatomy, physiology, histology, biochemistry, its museums, and some departments of the final years, such as forensic medicine and preventive medicine. .